Biodiversity Research Seminar Series (BRS)
BRS Christina Hodson: Evolution of germline restricted chromosomes and non-Mendelian inheritance in fungus gnats
November 16, 2022, 12:00 pm to 1:00 pm
Zoom webinar link for remote attendees:
https://ubc.zoom.us/j/66364136696?pwd=OVp2UW10Ulp5eCtncTVzQ3pvWmFZUT09
Passcode: 202209
host: Judith Mank
Title: Evolution of germline restricted chromosomes and non-Mendelian inheritance in fungus gnats
Abstract:
In eukaryotes, all cells within an individual generally have the same genetic
composition (i.e. DNA sequence). However, some animals have evolved an unusual
system of germline differentiation which involves parts of the genome being eliminated
from body cells and therefore being restricted to the germline. Fungus gnats are an
interesting example of this phenomenon, as these flies carry two entire chromosomes
that are restricted to the germline in adult flies. The germline restricted chromosomes
in fungus gnats are part of the unusual chromosome transmission system found in
these flies, which evolved approximately 50 million years ago and involves chromosome
elimination as a means of sex determination and parent of origin specific chromosome
transmission. How does this system, and specifically the germline restricted chromosomes,
evolve and how do the germline restricted chromosomes in fungus gnats compare to
other animals with germline restricted DNA? I will discuss work using genomic data to
characterise the content of the germline restricted chromosomes in fungus gnats, including
some surprising findings suggesting that these chromosomes evolved through introgression.
Dr. Hodson is a postdoctoral fellow studying in the Mank lab at UBC.